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Procedures for proper handling and disposal of potentially hazardous drugs should be considered.
COUMADIN is a racemic mixture of the Rand Senantiomers of warfarinThe Senantiomer exhibits 2 to 5 times more anticoagulant activity than the R-enantiomer in humansbut generally has a more rapid clearance.
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in patients with acquired or inherited warfarin resistance, decreased therapeutic responses to coumadin have been reported.