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Following a number of adverse event reports submitted over the first few years januvia was on the market, the fda required an update to the medications warning label in september 2009, providing information about the link between januvia and pancreatitis.

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It may not be safe to breast-feed a baby while you are using this medicineAsk your doctor about any risks.

Before you start taking JANUVIAtell your doctor if you haveever had heart failureyour heart does not pump blood well enoughor have problems with your kidneysContact your doctor right away if you have increasing shortness of breath or trouble breathingespecially when you lie downswelling or fluid retentionespecially in the feetanklesor legsan unusually fast increase in weightor unusual tirednessThese may be symptoms of heart failure.

If you take JANUVIA with another medicine that can cause low blood sugarsuch as a sulfonylurea or insulinyour risk of getting low blood sugar is higherThe dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUVIA.

Some people who take medicines called DPP-4 inhibitors like JANUVIA may develop a skin reaction called bullous pemphigoid that can require treatment in a hospitalTell your doctor right away if you develop blisters or the breakdown of the outer layer of your skinerosionYour doctor may tell you to stop taking JANUVIA.

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